Tires with a specified direction of rotation have additional benefits, e.g. if there is a risk of hydroplaning. You will only gain these benefits if the correct direction of rotation is observed.
An arrow on the sidewall of the tire indicates its correct direction of rotation.
You may mount the spare wheel against the direction of rotation. Adhere to the time restriction on use as well as the speed limitation specified on the spare wheel.
Trailer loads
Trailer drawbar noseweight
...
Tire tread
WARNING
Although the applicable federal motor vehicle
safety laws consider a tire to be worn when
the treadwear indicators (TWI) become visible
at approximately 1/16 inches (1.6 mm), we
recommend ...
Loading guidelines
WARNING
Always fasten items being carried as securely
as possible using cargo tie-down rings and
fastening materials appropriate for the weight
and size of the load.
In an accident, during hard ...